Experimental sciences rely on technical methods in the case of clinical pharmacology methods are often used that have been developed by other disciplines such as analytical chemistry eg high performance liquid chromatography gas chromatography mass spectrometry biochemistry molecular biology . Clinical and experimental pharmacology and physiology provides a medium for the rapid online publication of original research papers rapid communications and technical papers on the results of clinical and experimental work in pharmacology and physiology reviews research highlights and news views are also published. The objective of this volume is to give an overview of the present state of the art of pediatric clinical pharmacology including developmental physiology pediatric specific pathology special tools and methods for development of drugs for children assessment of efficacy toxicity long term safety etc as well as regulatory and ethical knowledge and skills. Methods and findings in experimental and clinical pharmacology is an international peer reviewed journal publishing original scientific articles dealing with the evaluation of methodologies and results obtained during the scientific assessment of drugs in animals and humans. Research in experimental anesthetic pharmacology it was strongly felt that the par ticularities of anesthetic drug therapy discussed above require not only specific drugs but also very particular modes of their delivery and administration it is not only the properties of the compounds but the combination of compounds plus drug
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